- Mauricio Perroud, Helen Honma, Aristoteles Barbeiro, Simone Gilli, Maria Almeida, Jose Vassallo, Sara Saad, Lair Zambon
Mature Autologous Dendritic Cell Vaccines in Advanced Non-Small Cell Lung Cancer: a Phase I Pilot Study
Credits/Source: Journal of Experimental &Clinical Cancer Research 2011, 30:65
Published on: 2011-06-17 - Sandy Van
Latest data from Cedars-Sinai vaccine study supports immune targeting of brain tumors
Public release date: 15-Jun-2011 - Cannon MJ, Goyne H, Stone PJ, Chiriva-Internati M.
Dendritic cell vaccination against ovarian cancer–tipping the Treg/TH17 balance to therapeutic advantage?
Expert Opin Biol Ther. 2011 Apr;11(4):441-5. Epub 2011 Jan 28. Review.
PMID:21271951[PubMed - indexed for MEDLINE] - Turnis ME, Rooney CM.
Enhancement of dendritic cells as vaccines for cancer.
Immunotherapy. 2010 Nov;2(6):847-62. Review.
PMID:21091116[PubMed - indexed for MEDLINE] - O’Neill DW.
Dendritic cells and T cells in immunotherapy.
J Drugs Dermatol. 2010 Nov;9(11):1383-92. Review.
PMID:21061761[PubMed - indexed for MEDLINE] - Rolinski J, Hus I.
Dendritic-cell tumor vaccines.
Transplant Proc. 2010 Oct;42(8):3306-8. Review.
PMID:20970677[PubMed - indexed for MEDLINE] - Vauleon E, Avril T, Collet B, Mosser J, Quillien V.
Overview of cellular immunotherapy for patients with glioblastoma.
Clin Dev Immunol. 2010;2010. pii: 689171. Epub 2010 Oct 4. Review.
PMID:20953324[PubMed - indexed for MEDLINE] - Merika E, Saif MW, Katz A, Syrigos K, Morse M.
Review. Colon cancer vaccines: an update.
In Vivo. 2010 Sep-Oct;24(5):607-28. Review. Erratum in: In Vivo. 2010 Nov-Dec;24(6):905. Syrigos, C [corrected to Syrigos, K]. Review.
PMID:20952724[PubMed - indexed for MEDLINE] - Aldrich JF, Lowe DB, Shearer MH, Winn RE, Jumper CA, Kennedy RC.
Vaccines and immunotherapeutics for the treatment of malignant disease.
Clin Dev Immunol. 2010;2010:697158. Epub 2010 Sep 26. Review.
PMID:20936120[PubMed - indexed for MEDLINE] - Dietrich PY, Dutoit V, Tran Thang NN, Walker PR.
T-cell immunotherapy for malignant glioma: toward a combined approach.
Curr Opin Oncol. 2010 Nov;22(6):604-10. Review. Review.
PMID:21271951[PubMed - indexed for MEDLINE] - Papewalis C, Ehlers M, Schott M.
Advances in cellular therapy for the treatment of thyroid cancer.
J Oncol. 2010;2010:179491. Epub 2010 Jun 29. Review.
PMID:20671939[PubMed - indexed for MEDLINE] - Soliman H.
Developing an effective breast cancer vaccine.
Cancer Control. 2010 Jul;17(3):183-90. Review.
PMID:20664516[PubMed - indexed for MEDLINE] - Pajtasz-Piasecka E, Indrová M.
Dendritic cell-based vaccines for the therapy of experimental tumors.
Immunotherapy. 2010 Mar;2(2):257-68. Review.
PMID:20635932[PubMed - indexed for MEDLINE] - van den Ancker W, van Luijn MM, Westers TM, Bontkes HJ, Ruben JM, de Gruijl TD, Ossenkoppele GJ, van de Loosdrecht AA.
Recent advances in antigen-loaded dendritic cell-based strategies for treatment of minimal residual disease in acute myeloid leukemia.
Immunotherapy. 2010 Jan;2(1):69-83. Review.
PMID:20635890[PubMed - indexed for MEDLINE] - Alexandrescu DT, Ichim TE, Riordan NH, Marincola FM, Di Nardo A, Kabigting FD, Dasanu CA.
Immunotherapy for melanoma: current status and perspectives.
J Immunother. 2010 Jul-Aug;33(6):570-90. Review.
PMID:20551839[PubMed - indexed for MEDLINE] - Moschella F, Proietti E, Capone I, Belardelli F.
Combination strategies for enhancing the efficacy of immunotherapy in cancer patients.
Ann N Y Acad Sci. 2010 Apr;1194:169-78. Review.
PMID:20536466[PubMed - indexed for MEDLINE] - Barrett AJ, Le Blanc K.
Immunotherapy prospects for acute myeloid leukaemia.
Clin Exp Immunol. 2010 Aug;161(2):223-32. Epub 2010 May 31. Review.
PMID:20529084[PubMed - indexed for MEDLINE] - Korangy F, Höchst B, Manns MP, Greten TF.
Immunotherapy of hepatocellular carcinoma.
Expert Rev Gastroenterol Hepatol. 2010 Jun;4(3):345-53. Review.
PMID:20528121[PubMed - indexed for MEDLINE] - Sabado RL, Bhardwaj N.
Directing dendritic cell immunotherapy towards successful cancer treatment.
Immunotherapy. 2010 Jan;2(1):37-56. Review.
PMID:20473346[PubMed - indexed for MEDLINE] - Chiappori AA, Soliman H, Janssen WE, Antonia SJ, Gabrilovich DI.
INGN-225: a dendritic cell-based p53 vaccine (Ad.p53-DC) in small cell lung cancer: observed association between immune response and enhanced chemotherapy effect.
Expert Opin Biol Ther. 2010 Jun;10(6):983-91. Review.
PMID:20420527[PubMed - indexed for MEDLINE] - Janikashvili N, Larmonier N, Katsanis E.
Personalized dendritic cell-based tumor immunotherapy.
Immunotherapy. 2010 Jan;2(1):57-68. Review.
PMID:20161666[PubMed - indexed for MEDLINE] - Viaud S, Théry C, Ploix S, Tursz T, Lapierre V, Lantz O, Zitvogel L, Chaput N.
Dendritic cell-derived exosomes for cancer immunotherapy: what’s next?
Cancer Res. 2010 Feb 15;70(4):1281-5. Epub 2010 Feb 9. Review.
PMID:20145139[PubMed - indexed for MEDLINE] - Ilett EJ, Prestwich RJ, Melcher AA.
The evolving role of dendritic cells in cancer therapy.
Ilett EJ, Prestwich RJ, Melcher AA. Review.
PMID:20132058[PubMed - indexed for MEDLINE] - Stavridi F, Karapanagiotou EM, Syrigos KN.
Targeted therapeutic approaches for hormone-refractory prostate cancer.
Cancer Treat Rev. 2010 Apr;36(2):122-30. Epub 2010 Jan 27. Review.
PMID:20106600[PubMed - indexed for MEDLINE] - Eksioglu EA, Eisen S, Reddy V.
Dendritic cells as therapeutic agents against cancer.
Front Biosci. 2010 Jan 1;15:321-47. Review.
PMID:20036823[PubMed - indexed for MEDLINE] - Frazier JL, Han JE, Lim M, Olivi A.
Immunotherapy combined with chemotherapy in the treatment of tumors.
Neurosurg Clin N Am. 2010 Jan;21(1):187-94. Review.
PMID:19944977[PubMed - indexed for MEDLINE] - Van Gool S.
The dendritic therapy with its potential applications in pancreatic cancer.
Acta Gastroenterol Belg. 2009 Jul-Sep;72(3):338-43. Review. No abstract available.
PMID:19902868[PubMed - indexed for MEDLINE] - Eubel J, Enk AH.
Dendritic cell vaccination as a treatment modality for melanoma.
Expert Rev Anticancer Ther. 2009 Nov;9(11):1631-42. Review.
PMID:19895246[PubMed - indexed for MEDLINE] - Yasukawa M.
[Immunotherapy and cell therapy for myeloid leukemia].
Nippon Rinsho. 2009 Oct;67(10):1938-43. Review. Japanese.
PMID:19860194[PubMed - indexed for MEDLINE] - Breckpot K, Escors D.
Dendritic cells for active anti-cancer immunotherapy: targeting activation pathways through genetic modification.
Endocr Metab Immune Disord Drug Targets. 2009 Dec;9(4):328-43.Review.
PMID:19857199[PubMed - indexed for MEDLINE] - Shumway NM, Ibrahim N, Ponniah S, Peoples GE, Murray JL.
Therapeutic breast cancer vaccines: a new strategy for early-stage disease.
BioDrugs. 2009;23(5):277-87. doi: 10.2165/11313490-000000000-00000. Review.
PMID:19754218[PubMed - indexed for MEDLINE] - Van Gool S, Maes W, Ardon H, Verschuere T, Van Cauter S, De Vleeschouwer S.
Dendritic cell therapy of high-grade gliomas.
Brain Pathol. 2009 Oct;19(4):694-712. Review.
PMID:19744041[PubMed - indexed for MEDLINE] - Grauer OM, Wesseling P, Adema GJ.
Immunotherapy of diffuse gliomas: biological background, current status and future developments.
Brain Pathol. 2009 Oct;19(4):674-93. Review.
PMID:19744040[PubMed - indexed for MEDLINE] - Yu Z, Ren P, Zhang X, Zhang T, Ma B.
Therapeutic potential of dendritic cell vaccines in sarcoma of the extremities.
Expert Rev Anticancer Ther. 2009 Aug;9(8):1065-71. Review.
PMID:19671026[PubMed - indexed for MEDLINE] - Palmer DH, Midgley RS, Mirza N, Torr EE, Ahmed F, Steele JC, Steven NM, Kerr DJ
Phase 2 study of adoptive immunotherapy using dendritic cells pulsed with tumor lysate in patients with hepatocellular carcinoma.
Hepatology. 2009 Jan;49(1):124-32. Review.
PMID:18980227[PubMed - indexed for MEDLINE] - Facchetti Lepisto AJ, Moser AJ, Zeh H, Lee K, Bartlett D, McKolanis JR, Geller BA
Dendritic vaccine as adjuvant therapy in patients with resected pancreatic and biliary tumors.
Cancer Ther. 2008;6(B):955-964. Review.
PMID:19129927[PubMed] PMCID: PMC2614325 - Burgdorf SK, Fischer A, Myschetzky PS, Munksgaard SB, Zocca MB
Responses in patients with advanced colorectal cancer to a dendritic cell based vaccine
Oncol Rep. 2008 Dec;20(6):1305-11. Review.
PMID:19020707[PubMed - indexed for MEDLINE] - Tanaka F, Haraguchi N, Isikawa K, Inoue H, Mori M.
Role of dendritic cell vaccination with MAGE peptides in gastrointestinal carcinoma
Oncol Rep. 2008 Nov;20(5):1111-6. Review.
PMID:18949409[PubMed - indexed for MEDLINE] - Shoua AB, Sergienco NF, Sitnikov NV, Chkadua GZ.
Trial of dendritic cell vaccines loaded with tumor antigens in the treatment of bladder cancer
Urologiia. 2008 Sep-Oct;(5):54-7. Review.
PMID:19069498[PubMed - indexed for MEDLINE] - Koski GK, Cohen PA, Roses RE, Xu S, Czerniecki, BJ.
Reengineering dendritic cell-based anti-cancer vaccines.
Immunol Rev. 2008 Apr;222:256-76. Review.
PMID:18364007[PubMed - indexed for MEDLINE] - Kalani AD, Jack A, Montenegro G, Degliuomini J, Wallack MK.
Immunotherapy as an adjuvant therapy in the management of advanced, surgically resected, melanoma
G Ital Dermatol Venereol. 2008 Feb;143(1):59-70. Review.
PMID:18833052[PubMed - indexed for MEDLINE] - John M. Timmerman, Debra K. Czerwinski, Thomas A. Davis, Frank J. Hsu, Claudia Benike, et al.
Idiotype-pulsed dendritic cell vaccination for B-cell lymphoma: clinical and immune responses in 35 patients. - T. Nesselhut , R. Y. Chang, C. Matthes, D. Marx, D. R. Lorenzen, N. Cillien, M. Martin, R. Gorter, J. H. Peters
Cancer therapy with unloaded monocyte-derived dendritic cells in patients with inoperable pancreatic and gall bladder cancer. - Figdor CG, de Vries IJ, Lesterhuis WJ, Melief CJ.
Dendritic cell immunotherapy: mapping the way.
Nat Med. 2004 May;10(5):475-80. Review.
PMID: 15122249 [PubMed - indexed for MEDLINE] - Cranmer LD, Trevor KT, Hersh EM.
Clinical applications of dendritic cell vaccination in the treatment of cancer.
Cancer Immunol Immunother. 2004 Apr;53(4):275-306. Epub 2003 Nov 26. Review.
PMID: 14648069 [PubMed - indexed for MEDLINE] - Nagaraj S, Ziske C, Schmidt-Wolf IG.
Dendritic cell, the immunotherapeutic cell for cancer.
Indian J Med Res. 2004 Apr;119:133-8. Review.
PMID: 15147117 [PubMed - indexed for MEDLINE] - Kawakami Y, Okada T, Akada M.
Development of immunotherapy for pancreatic cancer.
Pancreas. 2004 Apr;28(3):320-5. Review.
PMID: 15084980 [PubMed - indexed for MEDLINE] - Lotze MT, Rees RC.
Identifying biomarkers and surrogates of tumors (cancer biometrics): correlation with immunotherapies and immune cells.
Cancer Immunol Immunother. 2004 Mar;53(3):256-61. Epub 2004 Jan 21. Review.
PMID: 14735318 [PubMed - indexed for MEDLINE] - Whiteside TL, Odoux C.
Dendritic cell biology and cancer therapy.
Cancer Immunol Immunother. 2004 Mar;53(3):240-8. Epub 2003 Dec 18. Review.
PMID: 14685779 [PubMed - indexed for MEDLINE] - Bitton RJ.
Cancer vaccines: a critical review on clinical impact.
Curr Opin Mol Ther. 2004 Feb;6(1):17-26. Review.
PMID: 15011777 [PubMed - indexed for MEDLINE] - Cannon MJ, Santin AD, O’Brien TJ.
Immunological treatment of ovarian cancer.
Curr Opin Obstet Gynecol. 2004 Feb;16(1):87-92. Review.
PMID: 15128013 [PubMed - indexed for MEDLINE] - Santiago-Schwarz F.
Dendritic cells: friend or foe in autoimmunity?
Rheum Dis Clin North Am. 2004 Feb;30(1):115-34. Review.
PMID: 15061571 [PubMed - indexed for MEDLINE] - Redlinger RE Jr, Mailliard RB, Barksdale EM Jr.
Neuroblastoma and dendritic cell function.
Semin Pediatr Surg. 2004 Feb;13(1):61-71. Review.
PMID: 14765372 [PubMed - in process] - Moron G, Dadaglio G, Leclerc C.
New tools for antigen delivery to the MHC class I pathway.
Trends Immunol. 2004 Feb;25(2):92-7. Review.
PMID: 15102368 [PubMed - indexed for MEDLINE] - Turtle CJ, Hart DN.
Dendritic cells in tumor immunology and immunotherapy
Curr Drug Targets. 2004 Jan;5(1):17-39. Review.
PMID: 14738216 [PubMed - indexed for MEDLINE] - Cerundolo V, Hermans IF, Salio M.
Dendritic cells: a journey from laboratory to clinic.
Nat Immunol. 2004 Jan;5(1):7-10. Review. No abstract available.
PMID: 14699398 [PubMed - indexed for MEDLINE] - Vicari AP, Vanbervliet B, Massacrier C, Chiodoni C, Vaure C, Ait-Yahia S, Dercamp C, Matsos F, Reynard O, Taverne C, Merle P, Colombo MP, O’Garra A, Trinchieri G, Caux C.
In vivo manipulation of dendritic cell migration and activation to elicit antitumour immunity.
Novartis Found Symp. 2004;256:241-54; discussion 254-69. Review.
PMID: 15027495 [PubMed - indexed for MEDLINE] - Mantovani A, Sozzani S, Locati M, Schioppa T, Saccani A, Allavena P, Sica A.
Infiltration of tumours by macrophages and dendritic cells: tumour-associated macrophages
as a paradigm for polarized M2 mononuclear phagocytes.
Novartis Found Symp. 2004;256:137-45; discussion 146-8, 259-69. Review.
PMID: 15027487 [PubMed - indexed for MEDLINE] - Ponsaerts P, Van Tendeloo VF, Berneman ZN.
Cancer immunotherapy using RNA-loaded dendritic cells.
Clin Exp Immunol. 2003 Dec;134(3):378-84. Review.
PMID: 14632740 [PubMed - indexed for MEDLINE] - Fishman MN, Antonia SJ.
Cell-based immune therapy for metastatic renal cancer.
Expert Rev Anticancer Ther. 2003 Dec;3(6):837-49. Review.
PMID: 14686706 [PubMed - indexed for MEDLINE] - Seo N, Furukawa F, Tokura Y, Takigawa M.
Vaccine therapy for cutaneous T-cell lymphoma.
Hematol Oncol Clin North Am. 2003 Dec;17(6):1467-74. Review.
PMID: 14710897 [PubMed - indexed for MEDLINE] - Facchetti F, Vermi W, Mason D, Colonna M.
The plasmacytoid monocyte/interferon producing cells.
Virchows Arch. 2003 Dec;443(6):703-17. Epub 2003 Oct 28. Review. No abstract available.
PMID: 14586652 [PubMed - indexed for MEDLINE] - Hermans IF, Chong TW, Palmowski MJ, Harris AL, Cerundolo V.
Synergistic effect of metronomic dosing of cyclophosphamide combined with specific antitumor immunotherapy in a murine melanoma model.
Cancer Res. 2003 Dec 1;63(23):8408-13. Review.
PMID: 14679003 [PubMed - indexed for MEDLINE] - Mitchell MS.
Combinations of anticancer drugs and immunotherapy.
Cancer Immunol Immunother. 2003 Nov;52(11):686-92. Epub 2003 Aug 26. Review.
PMID: 12942200 [PubMed - indexed for MEDLINE] - Deng L, Ding W, Granstein RD.
Thalidomide inhibits tumor necrosis factor-alpha production and antigen presentation by Langerhans cells.
J Invest Dermatol. 2003 Nov;121(5):1060-5. Review.
PMID: 14708607 [PubMed - indexed for MEDLINE] - Juedes AE, Von Herrath MG.
Using regulatory APCs to induce/maintain tolerance.
Ann N Y Acad Sci. 2003 Nov;1005:128-37. Review.
PMID: 14679047 [PubMed - indexed for MEDLINE] - Seya T, Akazawa T, Uehori J, Matsumoto M, Azuma I, Toyoshima K.
Role of toll-like receptors and their adaptors in adjuvant immunotherapy for cancer.
Anticancer Res. 2003 Nov-Dec;23(6a):4369-76. Review.
PMID: 14666723 [PubMed - indexed for MEDLINE] - Wojas K, Tabarkiewicz J, Rolinski J.
Dendritic cells in cancer immunotherapy – a short review.
Folia Morphol (Warsz). 2003 Nov;62(4):317-8. Review.
PMID: 14655109 [PubMed - indexed for MEDLINE] - Hauser H, Chen SY.
Augmentation of DNA vaccine potency through secretory heat shock protein-mediated antigen targeting.
Methods. 2003 Nov;31(3):225-31. Review.
PMID: 14511955 [PubMed - indexed for MEDLINE] - Geissler M, Mohr L, Ali MY, Grimm CF, Ritter M, Blum HE.
Immunobiology and gene-based immunotherapy of hepatocellular carcinoma.
Z Gastroenterol. 2003 Nov;41(11):1101-10. Review.
PMID: 14648380 [PubMed - indexed for MEDLINE] - Jager E, Jager D, Knuth A.
Antigen-specific immunotherapy and cancer vaccines.
Int J Cancer. 2003 Oct 10;106(6):817-20. Review.
PMID: 12918057 [PubMed - indexed for MEDLINE] - McIlroy D, Gregoire M.
Optimizing dendritic cell-based anticancer immunotherapy: maturation state does have clinical impact.
Cancer Immunol Immunother. 2003 Oct;52(10):583-91. Epub 2003 Jun 24. Review.
PMID: 12827310 [PubMed - indexed for MEDLINE] - Indar AA, Maxwell-Armstrong CA.
Active specific immunotherapy for colorectal cancer.
Expert Rev Anticancer Ther. 2003 Oct;3(5):685-94. Review.
PMID: 14599091 [PubMed - indexed for MEDLINE] - Berger CL, Edelson RL.
Current concepts of the immunobiology and immunotherapy of cutaneous T cell lymphoma: insights gained through cross-talk between the clinic and the bench.
Leuk Lymphoma. 2003 Oct;44(10):1697-703. Review.
PMID: 14692521 [PubMed - indexed for MEDLINE] - Kaminski ER, Goddard RV, Prentice AG.
Dendritic cells and their potential therapeutic role in haematological malignancy.
Leuk Lymphoma. 2003 Oct;44(10):1657-66. Review.
PMID: 14692516 [PubMed - indexed for MEDLINE] - Kanazawa M, Mori Y, Yoshihara K, Iwadate M, Suzuki S, Endoh Y, Takita K, Sekikawa K, Takenoshita S, Ogata T, Ohto H.
[Effect of DC therapy combined with chemotherapy in advanced cancer cases]
Gan To Kagaku Ryoho. 2003 Oct;30(11):1655-60. Review. Japanese.
PMID: 14619487 [PubMed - indexed for MEDLINE] - Galamb O, Molnar B, Tulassay Z.
[Immunobiology of dendritic cells and their application in clinical practice]
Orv Hetil. 2003 Sep 21;144(38):1873-9. Review. Hungarian.
PMID: 14596026 [PubMed - indexed for MEDLINE] - Hernando JJ, Park TW, Kuhn WC.
Dendritic cell-based vaccines in breast and gynaecologic cancer.
Anticancer Res. 2003 Sep-Oct;23(5b):4293-303. Review.
PMID: 14666641 [PubMed - indexed for MEDLINE] - Dar MM, Kwak LW.
Vaccination strategies for lymphomas.
Curr Oncol Rep. 2003 Sep;5(5):380-6. Review.
PMID: 12895388 [PubMed - indexed for MEDLINE] - Yamanaka R, Homma J, Yajima N, Tsuchiya N, Tanaka R.
[Dendritic cell therapy for malignant glioma]
No To Shinkei. 2003 Sep;55(9):771-80. Review. Japanese.
PMID: 14571839 [PubMed - indexed for MEDLINE] - Mantovani A, Schioppa T, Biswas SK, Marchesi F, Allavena P, Sica A.
Tumor-associated macrophages and dendritic cells as prototypic type II polarized myeloid populations.
Tumori. 2003 Sep-Oct;89(5):459-68. Review.
PMID: 14870765 [PubMed - indexed for MEDLINE]
